Resources
Resources to help build a stronger science-based community.
Our Publications
Based on years of research, the Frestedt Incorporated team publishes numerous books, articles and clinical trial documents. If you need help dealing with (or avoiding) an FDA warning letter or if you are struggling with clinical evaluations or safety reporting for your drug, device or food product, please contact us. We’re here and ready to help!
Featured Publications

HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults.
Zenk JL, Frestedt JL, Kuskowski MA Link to publication Link to download PDF

AF4 encodes a ubiquitous protein that in both native and MLL-AF4 fusion types localizes to subnuclear compartments.
Li Q, Frestedt JL, Kersey JH Link to publication Link to download PDF

MLL gene rearrangement, cytogenetic 11q23 abnormalities, and expression of the NG2 molecule in infant acute myeloid leukemia.
Hilden JM, Smith FO, Frestedt JL, McGlennen R, Howells WB, Sorensen PH, Arthur DC, Woods WG, Buckley J, Bernstein ID,

Molecular analysis of infant acute leukemia
Hilden JM, Frestedt JL, Kersey JH Link to publication Link to download PDF

AF4/FEL, a gene involved in infant leukemia: sequence variations, gene structure, and possible homology with a genomic sequence on 5q31.
Frestedt JL, Hilden JM, Kersey JH Link to publication Link to download PDF

Rearrangement of the MLL gene confers a poor prognosis in childhood acute lymphoblastic leukemia, regardless of presenting age
Behm FG, Raimondi SC, Frestedt JL, Liu Q, Crist WM, Downing JR, Rivera GK, Kersey JH, Pui CH Link to

Differential expression of AF4/FEL mRNA in human tissues
Frestedt JL, Hilden JM, Moore RO, Kersey JH Link to publication Link to download PDF

Acute lymphoblastic leukemias with deletion of 11q23 or a novel inversion (11)(p13q23) lack MLL gene rearrangements and have favorable clinical features
Raimondi SC, Frestedt JL, Pui CH, Downing JR, Head DR, Kersey JH, Behm FG Link to publication Link to download

Heterogeneity in MLL/AF-4 fusion messenger RNA detected by the polymerase chain reaction in t(4;11) acute leukemia
Hilden JM, Chen CS, Moore R, Frestedt J, Kersey JH Link to publication Link to download PDF

The chromosome 4q21 gene (AF-4/FEL) is widely expressed in normal tissues and shows breakpoint diversity in t(4;11)(q21;q23) acute leukemia
Chen CS, Hilden JM, Frestedt J, Domer PH, Moore R, Korsmeyer SJ, Kersey JH Link to publication Link to download
